Research Grant Recipients

Sophia Y Wang, MD | Byers Eye Institute, Stanford University  

An Image Worth a Thousand Words?  Multimodal Data Fusion for Personalized Glaucoma Predictions Using Electronic Health Records

Inas F. Aboobkaar, MD | Massachusetts Eye and Ear

Correlation of genome-wide and pathway-specific POAG polygenic risk scores with disease-defining clinical features

Natasha Nayak Kolomeyer, MD  | Willis Eye Hospital 

Fighting for the second eye: Understanding and preventing sequential blindness in patients with glaucoma

Jiun Lap Do, MD, PHD | University of California, San Diego 

Stem Cell-Derived Optic Nerve Relays to Restore Vision

Wendy Wing-Heng Liu, MD, PHD | Stanford University

Functional Characterization of Mechanosensitive Ion Channels in the Eye and Their Role in Glaucoma

Nazlee Zebardast MD MSC | Massachusetts Eye and Ear/Harvard Medical School

Predicting Glaucoma Progression Using Genetic Risk Variants, Machine Learning Derived Phenotypes, and Clinical Features

Thomas V. Johnson III, MD, PhD | Wilmer Eye Institute, Johns Hopkins University School of Medicine

Development and Validation of a Novel Reporter System to Identify Synaptic Integration of Transplanted Retinal Ganglion Cells

Preethi S. Ganapathy, MD, PhD | SUNY Upstate Medical University

The Role of Mechanosensitive Channel Activity in TGFβ2-Mediated Astrocyte Dysfunction

Lucy Q Shen, MD | Mass Eye and Ear

Assessing T Cells in Patients with Progressive Vision Loss from Glaucoma

Shandiz Tehrani, MD, PHD | Casey Eye Institute, Oregon Health & Science University

Modulation of Optic Nerve Astrocytes in Glaucoma

Ahmara G Ross, MD, PHD | Scheie Eye Institute/University of Pennsylvania

Characterization and Therapeutic Intervention using the WDR36 Gene in a Mouse Model of Glaucoma

Benjamin Xu, MD, PHD  | University of Southern California Roski Eye Institute

Anatomical Mechanisms for Development and Progression of Primary Angle Closure Disease: A Cross-Sectional and Longitudinal Analysis

Tave Van Zyl, MD | Mass Eye and Ear / Harvard Medical School

Transcriptomic Characterization of Human Retinal Pathology in Glaucoma

Ken Y Lin, MD, PHD | University of California, Irvine

Development of a contrast-enhanced laser and ultrasound prototype imaging device for ab interno imaging of the aqueous outflow pathway

Supported by: Bausch + Lomb

Gavin W Roddy, MD, PhD | Mayo Clinic

Investigating STC-1 as a targeted intraocular pressure lowering therapy involved in prostaglandin analogue signaling

Supported by: Allergan

Erin A Boese, MD | The University of Iowa

The Molecular Genetics of Primary Congenital Glaucoma

Supported by: AGS Foundation

Grace M. Richter, MD, MPH | USC Roski Eye Institute, Keck School of Medicine of University of Southern California

Detecting Retinal Microcirculation Changes after Intraocular Pressure Reduction in Glaucoma

Supported by: Bausch + Lomb

Qi N. Cui, MD, PhD | Scheie Eye Institute, University of Pennsylvania

Mitochondrial Respiratory Chain Dysfunction in Primary Open Angle Glaucoma

Supported by: AGS Foundation

Brian Song, MD | Mass. Eye and Ear Infirmary, Harvard Medical School

Glaucoma Detection in Diabetes Teleretinal Programs

Supported by: AGS Foundation

Nathaniel C. Sears, MD | Department of Ophthalmology and Visual Sciences, University of Iowa

Making and Characterizing a Hybrid Genetic / Experimental Mouse Model of Glaucoma

Supported by: Allergan

Ian Pitha, MD, PhD | Johns Hopkins University Targeting scleral

Fibroblast Transdifferentiation for Glaucoma Neuroprotection

Supported by: AGS Foundation - Allergan Award

Osamah J. Saeedi, MD | University of Maryland

Autoregulation of Ocular Blood Flow: The Effect of Altering Ocular Perfusion Pressure on Erythrocyte Dynamics in a Non-Human Primate Model

Supported by: AGS Foundation - Bausch + Lomb Award

Paula Anne Newman Casey, MD | University of Michigan

A Counseling Training Program for Glaucoma Staff: Development and Preliminary Assessment

Supported by: AGS Foundation - Alcon Award

Scott D. Lawrence, MD | University of North Carolina at Chapel Hill

Title: Nanoparticle-Based Delivery of siRNA for Glaucoma

Supported by: Alcon and AGSF

James C.H. Tan, MD, FRCOphth, PhD | Doheny Eye Institute

Title: Imaging Human Trabecular Meshwork Cell Biology and Pharmacology

Supported by: Merck and AGSF

Benjamin J. Frankfort, MD, PhD | Baylor College of Medicine

Title: Retinal Dysfunction in Mouse Models of Acute and Chronic Experimental Glaucoma

Supported by: Allergan and AGSF

Teresa C. Chen, MD | Massachusetts Eye and Ear Infirmary

Title: Spectral Domain Optical Coherence Tomography (OCT) 3D Neuroretinal Rim Analysis of the Optic Nerve Head

Supported by: AGS

Thasarat S. Vajaranant, MD | University of Illinois at Chicago

Title: A Feasibility Study to Access the Accuracy of Self-Reported Outcomes and Participant Interest in Ancillary Glaucoma Studies as Part of the Women's Health Initiative (WHI) Extension

Supported by: Valeant and AGS

Rachel W. Kuchtey, MD, PhD | Vanderbilt Eye Institute

Title: Investigation of Microfibril Genes in POAG

Supported by: Alcon and AGSF

Lucy Q. Shen, MD | Massachusetts Eye and Ear Infirmary

Title: Using Structure-Function Relationship to Aid the Diagnosis and Monitoring of Glaucoma

Supported by: Alcon

Yvonne Ou, MD | University of California, San Francisco

Title: Synapse Loss in a Mouse of Ocular Hypertension

Supported by: Merck

John Danias, MD | SUNY Downstate

Title: Development of an Artificial Trabecular Meshwork

Supported by: Alcon

John H. Fingeret, MD | Carver College of Medicine, University of Iowa

Title: Generating an Animal Model of Normal Tension in Glaucoma

Supported by: Allergan

Kathryn E. Bollinger, MD, PhD | Medical College of Georgia

Title: Molecular Mechanisms of Sigma Receptor 1 Mediated Neuroprotection

Supported by: Alcon

Nils A. Loewen, MD, PhD | Yale University

Title: Engineering of de novo Trabecular Meshwork

Supported by: Allergan

Kelly W. Muir, MD | Duke University

Title: Improving the Measurement of Glaucoma Medication Adherence

Supported by: Merck

Kouros Nouri-Mahdavi, MD | Jules Stein Eye Institute

Title: Optimizing Imaging of the Retinal Nerve Fiber Layer with Spectral-Domain Optical Coherence Tomography

Supported by: AGS

Yang Sun, MD, PhD | Indiana University

Title: Domain Optical Coherence Tomography

Supported by: AGS

Anjali Bhorade, MD | Washington University, St. Louis

Title: Validation of a Driving Simulator to Detect Unsafe Driving in Glaucoma Patients

Supported by: Alcon

Richard K. Lee, MD, PhD | Bascom Palmer Eye Institute

Title: Molecular Composition of Pseudoexfoliation Material

Supported by: Allergan

Brian Christopher Samuels MD, PhD | Indiana University

Title: Development of a New Experimental Model of Glaucoma in Rats via Reduction of Intracerebral Pressure

Supported by: The Glaucoma Foundation

Vikas Gulati, MD | University of Nebraska

Title: Effects of Selective Laser Trabeculoplasty on Aqueous Humor Dynamics

Supported by: Alcon

Christopher C. Teng, MD | New York Eye and Ear

Title: Determining Relationships Between Optic Nerve Parameters and Rates of Visual Field Progression in Patients with Beta-Zone Parapapillary Atrophy

Supported by: Allergan

Molly M. Walsh, MD, MPH | Duke Eye Center

Title: Global Gene Expression and Protein Profiling of Retinas Exposed to Elevated Intraocular Pressure

Supported by: Merck

Claude F. Burgoyne, MD | Devers Eye Institute, Oregon Health and Sciences University, Discoveries in Sight Research Laboratories

Title: Identifying the Proteomic Signature of the ONHs of Early Glaucomatous Non-Human Primate (NHP) Eyes

Supported by: Alcon

Felipe A. Medeiros, MD, PhD | Hamilton Glaucoma Center - University of California San Diego

Title: Development and Validation of a Combined Structural and Functional Index for Detection of Glaucoma

Supported by: Allergan

Anthony D. Realini, MD | West Virginia University Eye Institute

Title: The St. Lucia SLT Project

Supported by: Pfizer

Edward M. Barnett, MD, PhD | Washington University

Title: Cell-Penetrating Probes for Imaging Apoptosis in a Rodent Model of Retinal Ganglion Cell Degeneration

Supported by: Alcon

Cynthia L. Grosskreutz, MD, PhD | Harvard University - Mass. Eye & Ear Infirmary/Glaucoma

Title: Is Neuregulin-1 a Survival Factor for Retinal Ganglion Cells in Glaucoma?

Supported by: Allergan

Young H. Kwon, MD, PhD | University of Iowa Hospital and Clinic

Title: Automated method to determine cup and disc boundaries in 3D OCT images of the optic nerve

Supported by: AGS

Darrell WuDunn, MD, PhD | Indiana University

Title: An Integrated Approach to Identifying Signaling Pathways in Glaucoma

Supported by: Merck

Michael V. Boland, MD, PhD | Johns Hopkins Univerity - Wilmer Eye Institute

Title: Combined Index of Optic Nerve Structure and Function

Supported by: Alcon

Joshua D. Stein, MD, MS | University of Michigan

Title: Racial Disparities in the Care of Elderly Americans with Glaucoma

Supported by: Allergan

Donald L. Budenz, MD, MPH | Bascom Palmer Eye Institute

Title: Tema Eye Survey

Supported by: Alcon

Douglas J. Rhee, MD | Massachusetts Eye and Ear

Title: Functional Consequence of Matricellular Protein Deletion in Transgenic Mice Study of Hevin and Hevin/SPARC-Null Mice

Supported by: Allergan

Sanjay G. Asrani, MD | Duke University

Title: Evaluation of the Icare Rebound Tenometer as a Home Intraocular Pressure Monitoring Device

Supported by: Helen Keller Foundation

John H.Fingert, MD | University of Iowa

Title: Molecular Genetics of Pigment Dispersion Syndrome - Continuation Application

Supported by: Merck

Henry Tseng, MD, PhD | Duke University

Title: Disruption of Neuronal Protein Trafficking by Optineurin Mutations

Supported by: Allergan

Pradeep Y. Ramulu,MD, PhD | University of Illinois

Title: Reading Impairment in Subjects With Bilateral Glaucoma

Supported by: The Glaucoma Foundation

Thasarat S. Vajaranant, MD | Mayo Clinic

Title: Structural Testing in Advanced Glaucoma

Supported by: Alcon

Rachel W. Kuchtey, MD, PhD | Vanderbilt University

Title: Mechanisms of Regulation of Cornea-derived Transcript 6 Expression by Transforming Growth Factor Beta in Human Trabecular Meshwork Cells and Tissue

Supported by: Pfizer

Arthur J. Sit, MS,MD | Mayo Clinic

Title: Circadian Variation of Aqueous Humor Dynamics in Healthy Older Subjects

Supported by: AGS

John H. Fingert, MD, PhD | University of Iowa

Title: Molecular Genetics of Pigment Dispersion Syndrome

Supported by: The Glaucoma Foundation

Malik Y. Kahook, MD | University of Colorado

Title: The Effect of a Systemic Non-Selective Endothelin Antagonist on Intraocular Pressure and Anterior Chamber Depth in Pulmonary Hypertension Patients

Supported by: Allergan

Malik Y. Kahook, MD | University of Colorado

Title: Effect of Glaucoma Educators on Adherence to Prescribed Therapeutic Regimens in Glaucoma Patients

Pfizer – Compliance Grant

Rachel W. Kuchtey, MD, PhD | Vanderbilt University

Title: Mechanisms of Regulation of Cornea-Derived Transcript 6 Expression

Supported by: AGS

Felipe A. Medeiros, MD, PhD | Hamilton Eye Center – University of California San Diego

Title: The Relationship between Water-Drinking Provocative Test and 24-hour Intraocular Pressure Measurements

Supported by: Alcon

Arthur J. Sit, MS, MD | Mayo Clinic

Title: Circadian Variation of Aqueous Humor Dynamics in Healthy Older Subjects

Supported by: Merck

JoAnn A. Giaconi, MD | Jules Stein Eye Center - UCLA

Title: Nutritional Associations With Glaucoma Among Older African-American Women

Supported by: The Glaucoma Foundation

Anjali M. Bhorade, MD, MPH | Washington University

Title: Glaucoma and Visual Function

Supported by: Alcon

Sameer Imtiaz Ahmad, MD | Wilmer Eye Institute

Title: Glaucoma in the Himalayas: A Clinic-Based Survey in Kashmir, India

Supported by: Allergan

Steven L. Mansberger, MD, MPH | Devers Eye Institute

Title: Glaucoma Treatment Compliance Assessment Tool (GTCAT) Project

Supported by: Pfizer

Molly M. Walsh, MD, MPH | Duke University

Title: Monocyte-Derived Macrophages: Role in Pathophysiology of Glaucoma

Supported by: Merck

Shan C. Lin, MD | University of California, San Francisco

Title: Cytoskeletal Candidate Genes involved in Aqueous Outflow Obstruction

Supported by: The Glaucoma Foundation

Shan C. Lin, MD | University of California, San Francisco

Title: Cytoskeletal Candidate Genes involved in Aqueous Outflow Obstruction

Supported by: Alcon

Camille Hylton, MD | Emory Eye Clinic

Title: Investigation of the Molecular Basis of Outflow Obstruction in Primary Open Angle Glaucoma

Supported by: Allergan

Jeffrey A. Kammer, MD | Vanderbilt Eye Institute

Title: The Role of Fas Complex in Stress Related Retinal Ganglion Cell Death

Supported by: Pfizer Compliance Grant

Leslie S. Jones, MD | Howard University College of Medicine

Title: Genetic Risk Factors for Primary Open-Angle Glaucoma in an Urban African-American Population

Supported by: Merck

Douglas J. Rhee, MD | Wills Eye Hospital

Title: Latanoprost and Pirfenidone to Alter the MMP:TIMP Ratio in Trebecular Meshwork Endothelial and Ciliary Body Smooth Muscle Cells

Supported by: AGS

Christopher A. Girkin, MD, MSPH | University of Alabama

Title: Detection of Glaucoma Using Qualitative and Quantitative Assessment of the Optic Disc and Nerve Fiber Layer in African-Americans and Caucasians

Supported by: AGS

Steven L. Mansberger, MD, MPH | Devers Eye Institute

Title: The Northwest Tribal Healthy Vision Project

The Glaucoma Foundation

Richard K. Lee, MD, PhD | Bascom Palmer Eye Inst

Title: Characterization of Pseudoexfoliation Glaucoma Proteins

Supported by: Alcon

Douglas J. Rhee, MD | Wills Eye Hospital

Title: The Effect of Latanoprost on Tissue Inhibitors of Matrix Metalloproteinases (TIMPs) and Non-Constitutively Expressed Matrix Metalloproteinases in Trabecular Meshwork Endothelial and Ciliary Body Smooth Muscle Cells

Supported by: Allergan

Pratap Challa, MD | Duke University

Title: Pathogenesis of Pseudoexfoliation Syndrome

Supported by: Novartis

Steven L. Mansberger, MD, MPH | Devers Eye Institute

Title: The Northwest Tribal Healthy Vision Project (NTHVP)

Supported by: Pharmacia

Christopher A. Girkin, MD, MSPH | University of Alabama

Title: Detection of glaucoma using qualitative and quantitative assessment of the optic disc and nerve fiber layer in African-Americans and Caucasians

Supported by: Allergan

Edward M Barnett, MD, PhD | Washington University

Title: N/A

Supported by: Novartis

Margaret S. Spencer, MD | Mayo Clinic

Title: N/A

Supported by: Novartis

Stuart J. McKinnon, MD, PhD | University of Texas Health Science Center

Title: N/A

Supported by: Otsuka America Pharmaceuticals

Darrell WuDunn, MD. PhD | Indiana University

Title: Mechanotransduction in the Trabecular Meshwork

Supported by: Otsuka America Pharmaceuticals

Young H. Kwon, MD, PhD | University of Iowa

Title: Assessment of Alterations in Gene Expression in the Trabecular Meshwork and Ciliary Body of Donors with Glaucoma

Supported by: Otsuka America Pharmaceuticals

Deepak P. Edward, MD | UIC, Dept. of Ophthalmology

Title: N/A

Supported by: Otsuka America Pharmaceuticals